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US nears deal to fund Moderna's bird flu vaccine trial, FT reports

 

US nears deal to fund Moderna's bird flu vaccine trial, FT reports



May 30 (Reuters) - The U.S. government is nearing an agreement to fund a late-stage trial of Moderna's mRNA bird flu vaccine, the Financial Times reported on Thursday, as the outbreak spreads in dairy cows.
Moderna told Reuters it was in discussions with the government on advancing its vaccine candidate, but did not confirm the funding, saying it has nothing further to add.( )
Federal funding from the Biomedical Advanced Research and Development Authority (BARDA) could come as soon as next month and would include a promise to procure doses if late-stage trials are successful, the FT report said, citing people close to the discussions.
The U.S. Department of Health and Human Services (HHS) did not immediately respond to a Reuters' request for comment.
Moderna is testing the experimental shot, mRNA-1018, against several strains of the virus - including the currently circulating H5N1 variant. It said dosing in an early-to-mid stage study of the vaccine was completed, and it expects data soon.( )
Shares of the company have risen about 40% since April 1, when the second known human case of bird flu in the United States was reported. The stock was up about 3% at $151.25 in premarket trading on Thursday.
The United States has a stockpile of bird flu vaccines matched with the strain currently circulating, as well as antivirals that could be used to treat human infections. For a major epidemic or a pandemic, however, the country would have to considerably scale up stock.
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14 pro-democracy activists convicted, 2 acquitted in Hong Kong’s biggest national security case


14 pro-democracy activists convicted, 2 acquitted in Hong Kong’s biggest national security case



Fourteen pro-democracy activists were convicted in Hong Kong’s biggest national security case on Thursday by a court that said their plan to effect change through an unofficial primary election would have undermined the government’s authority and created a constitutional crisis.( )

After a 2019 protest movement that filled the city’s streets with demonstrators, authorities have all but silenced dissent in Hong Kong through reduced public choice in elections, crackdowns on media and the Beijing-imposed security law under which the activists were convicted.( )

Those found guilty of conspiracy to commit subversion included former lawmakers Leung Kwok-hung, Lam Cheuk-ting, Helena Wong and Raymond Chan, and they could face up to life in prison when sentenced later. The two defendants acquitted were former district councilors Lee Yue-shun and Lawrence Lau. But the prosecution said it intends to appeal against the acquittals.( )

The activists were among 47 democracy advocates who were prosecuted in 2021 for their involvement in the primary. Prosecutors had accused them of attempting to paralyze Hong Kong’s government and topple the city’s leader by securing the legislative majority necessary to indiscriminately veto budgets.( )

In a summary of the verdict distributed to media, the court said the election participants had declared they would “either actively use or use the power conferred on the (Legislative Council) by the (Basic Law) to veto the budgets.”

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Mets expected to DFA Jorge Lopez after he throws glove into stands, calls Mets 'worst' team in MLB

 

Mets expected to DFA Jorge Lopez after he throws glove into stands, calls Mets 'worst' team in MLB

The New York Mets have underperformed in 2024, and one of the team's top relievers has seemingly had enough. Following a 10-3 loss to the Los Angeles Dodgers, finishing off a sweep of the Mets, 2022 All-Star Jorge Lopez had this to say about his team.( )

OUCH! The worst team in MLB? It doesn't matter how bad your team is playing, you can't say that.

Lopez's emotions were obviously running high during this interview. Lopez had been ejected from the game for arguing a check swing call with the third base umpire. After the ejection, Lopez threw his glove into the stands in frustration, which manager Carlos Mendoza deemed "unacceptable."( )

Lopez ended the day having pitched just 0.1 innings, surrendering two earned runs on two hits and one walk.

What will happen to Lopez?

The Mets will DFA Lopez, according to multiple reports.( )

All things Mets: Latest New York Mets news, schedule, roster, stats, injury updates and more.

While the decision makes sense given what Lopez did and said, it's still a little shocking considering the success Lopez has had this season. In 2024, Lopez has posted a 3.12 ERA. He is one of only two relievers on the team to have pitched at least 20 innings while maintaining an ERA under 3.50.( )

What does DFA mean?

When a player is DFA'd (Designated for Assignment), he is immediately removed from the team's 40-man roster. The team then has seven days to either return the player to the 40-man roster, place them on waivers, trade them, release them, or send them down to the minor leagues.( )

Given Lopez's strong start to 2024, it would not be a shock for him to find a new team quickly should the Mets decide to place him on waivers or release him outright.( )

Are the Mets actually 'the worst team in baseball?'

Record-wise, no. The Mets have a better record than the Los Angeles Angels, Colorado Rockies, Miami Marlins, and Chicago White Sox, with the White Sox having the worst record in baseball at 15-41.

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Can BYU Afford $20M Annually in Athlete Revenue Share?

 

Can BYU Afford $20M Annually in Athlete Revenue Share?

Nov 19, 2022; Provo, Utah, USA; Brigham Young Cougars athletic director Tom Holmoe after a game against the Utah Tech Trailblazers at LaVell Edwards Stadium. Mandatory Credit: Rob Gray-USA TODAY Sports / Rob Gray-USA TODAY Sports

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Thursday was a historical day in the world of college sports. For the first time in over 100 years, the NCAA and the Power Five conferences agreed to allow schools to directly pay players. The agreement comes as part of a settlement for a handful of antitrust cases. As reported by ESPN, "The parties a have agreed to a revenue-sharing plan allowing each school to share up to roughly $20 million per year with its athletes."This major change will impact every Power Four team in the near future, including BYU. BYU could pay its athletes up to $20 million

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 annually in revenue share. That's, of course, if BYU can afford it.That significant "if" isn't unique to BYU. Schools across the country are concerned about the prospect of paying $20 million annually to their athletes. Not because they don't have enough revenue to go around - they certainly do. Over the last couple decades in college sports, however, major college athletic departments have been in an arms race to build the best facilities, hire the biggest staffs, and pay for every competitive advantage imaginable. If they've earned a dollar, they've spent that dollar. These athletic departments haven't been making a profit to pay shareholders - they've been spending everything they make in the name of winning.

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Can those schools really unwind those costs to absorb $20 million annually? Some simply will not be able to afford it. Most importantly, will BYU be able to afford it?

First and foremost, we know that BYU athletics is financially independent. They say as much on their website. "BYU Athletics is self-sustaining and receives no tithing or tax dollars to run its programs." Second, while we can't look at BYU's financials to confirm, it's pretty safe to assume that BYU does not spend more than they earn. That would go directly against the church's council to spend within your means. For the purpose of this article, we will assume that BYU has been spending within its means.

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